Linezolid vancomycin resistant Enterococcus isolated from clinical samples in Tehran hospitals.
Indian J Med Sci
;
2009 July; 63(7) 297-302
Article
in English
| IMSEAR
| ID: sea-145423
ABSTRACT
Background:
Vancomycin-resistant enterococci pose an emerging health risk. The limitation in therapeutic options has resulted in the development of new drugs such as quinupristin/ dalfopristin and linezolid. Aim, Setting andDesign:
This study investigated the species prevalence and antibacterial resistance among enterococci isolated in selected Tehran hospitals. Materials andMethods:
Between March 2006 and August 2007, 200 enterococcal isolates from urine, blood, stool and wound were recovered in 2 teaching hospitals of Tehran province. Susceptibility of all isolates was tested against vancomycin, teicoplanin and linezolid antibiotics by disk diffusion and agar dilution method. Results andConclusion:
Seventeen (8.5%), 6 (3%) and 4 (2%) of the isolates were resistant to vancomycin, teicoplanin and linezolid, respectively. Within the vancomycin-resistant isolates, 6 (35.2%), 4 (25%) and 1 (5.88%) showed vanA, vanB and vanC genotype patterns, respectively. Four (23.5%) of VRE isolates were resistant to linezolid with minimum inhibitory concentrations between 16 and 32 µg/mL. Two linezolid vancomycin resistant enterococci were E. faecium.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Microbial Sensitivity Tests
/
Serum Bactericidal Test
/
Prevalence
/
Gram-Positive Bacterial Infections
/
Enterococcus
/
Teicoplanin
/
Vancomycin Resistance
/
Oxazolidinones
/
Drug Resistance, Multiple, Bacterial
Type of study:
Prevalence study
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Med Sci
Year:
2009
Type:
Article
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