Effect of Naja naja Laurenti shed skin extract on estrous cycle, hormone - cytokine profiles, histopathology of ovary and uterus of Swiss albino mice.
Indian J Exp Biol
; 2013 Mar; 51(3): 235-240
Article
in En
| IMSEAR
| ID: sea-147587
ABSTRACT
The snake shed skin though considered as biological waste products have been mentioned in folk and traditional medicine for treatment of ailments like skin disorders, parturition problems etc. Shedded skin extract (5 mg.kg-1, sc) did not produce any change in the estrous cycle of normal cycling female mice. However in 10 mg.kg-1, sc dose, the extract caused a temporary cessation of the estrous cycle at diestrous phase in normal cycling female mice for 10 days. SSAE (10 mg.kg-1, sc) caused a significant change in the level of LH, FSH, progesterone, estradiol, IL-1β, IL-6 and TNF-α. Histopathology of uterus and ovary showed structural disorientation in both. The results substantiate the influence of snake shed skin in mice reproductive cycle.
Key words
Full text:
1
Index:
IMSEAR
Main subject:
Ovary
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Progesterone
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Reproduction
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Skin
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Uterus
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Female
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Gene Expression Regulation
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Cytokines
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Elapidae
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Estrous Cycle
Language:
En
Journal:
Indian J Exp Biol
Year:
2013
Type:
Article