Prospective evaluation of a rapid diagnostic test Typhidot for typhoid fever.
Article
in En
| IMSEAR
| ID: sea-16329
ABSTRACT
BACKGROUND & OBJECTIVE:
Typhoid fever still continues to be a major public health problem around the world. A simple, reliable and affordable rapid diagnostic test has been a long felt need of the clinicians. We therefore prospectively evaluated the sensitivity and specificity of Typhidot test.METHODS:
The study was carried out between January 2002 and December 2003, on a total of 563 samples from patients clinically suspected to have typhoid fever; blood culture as well as serum for Typhidot test were received.RESULTS:
Of the 563 samples, Typhidot test and blood culture were positive in 36 patients, both the tests were negative for 503 patients. Typhidot test was positive for 9 patients with S. Paratyphi A infection. The sensitivity and specificity of the test using blood culture as gold standard were 92.3 and 98.8 per cent respectively for the typhoid fever. INTERPRETATION &CONCLUSION:
Typhidot test is rapid, easy to perform and reliable test for diagnosing typhoid fever, useful for small less equipped laboratories as well as for those with better facilities.
Full text:
1
Index:
IMSEAR
Main subject:
Salmonella paratyphi A
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Salmonella typhi
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Time Factors
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Typhoid Fever
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Humans
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Enzyme-Linked Immunosorbent Assay
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Prospective Studies
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Sensitivity and Specificity
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Paratyphoid Fever
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False Negative Reactions
Type of study:
Diagnostic_studies
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Evaluation_studies
/
Observational_studies
Language:
En
Year:
2006
Type:
Article