Comparative Study of Prostaglandin F2 α Versus Ergometrine in the Management of Post Partum Haemorrhage

ABSTRACT

The present study was done to compare Prostaglandin F2 α (250μg) and methylergometrine (0.25mg) in the management of postpartum haemorrhage. 100 women of postpartum haemorrhage were studied in the tertiary care teaching hospital of Govt. Medical College Srinagar. at LDH in year 2001 to 2003. They were divided in two groups. Group A women were given intravenous methylgometrine (0.25mg) and group B received intramuscular injection of prostaglandin F2 α (250 μg). Main outcome measures were duration of third stage of labor, amount of blood loss and the side effects of drugs. Two groups were comparable with regard to parity in group A, 54% were primipara and 46% multipara; in group B 66% were primipare and 34% multipara. Mean duration of third stage of labour was shortened in group B. Blood loss was comparably less in group B (p < .001). Side effects were noted in both the groups but more in group A. Prostaglandin F2 ∝ (250μg) is a life saving drug in atonic postpartum haemorrhage, It shortens the duration of third stage of labour, and minimizes blood loss. Prostaglandin F2 ∝ offers an advantage over methylergometrine in case of hypertension.