Vitamin D Deficiency as a Factor Influencing Asthma Control in Children

ABSTRACT

Objective: To study the association between asthma control and serum 25OH Vitamin Dlevels in children with moderate persistent asthma on preventer therapy. Methods:Children aged 6-18 years, with moderate persistent asthma, on preventer therapy for ?2months were included. Control was categorized as good, partial or poor as per GINAguidelines. Serum 25 (OH) Vitamin D levels were measured and their relationship with thelevel of control was studied. Results: Out of 50 children enrolled, 22 had well-controlledasthma, and 21 had partially controlled asthma. Vitamin D was deficient in 30 children andinsufficient in 18 children. Children with vitamin D deficiency had significantly less well-controlled asthma as compared to those with insufficient or sufficient levels of 25 (OH)vitamin D (13.3% vs 88.9 % vs 100%). Conclusion: Vitamin D deficiency is associated withsuboptimal asthma control.