To Study Serum Testosterone Levels in Metabolic Syndrome

ABSTRACT

Introduction: Metabolic syndrome (Metabolic syndrome)is a complex disorder with high socioeconomic cost that isconsidered a worldwide epidemic. Current research aimed tostudy serum testosterone levels in metabolic syndrome.Material and methods: The present study was ProspectiveObservational study carried out at CSS Hospital, SubhartiMedical College Meerut U.P. 100 patients of metabolicsyndrome were included in the study who fulfilled the IDFcriteria of metabolic syndrome these patients underwentgenral examination, anthropometry,systemic examination,bmi was calculated, different investigation (Fasting LipidProfile, Serum Testosterone Levels,HBA1C, blood sugarlevels). Descriptive analysis of the collected data was done.Correlation of serum testosterone with various componentsof metabolic syndrome was studied using SPSS software tocalculate the level of significanceResults: This study confirmed the high prevalence of lowtestosterone levels in male patients with metabolic syndrome.The total number of patients who had BMI of more than 35 kg/m2, were 18 and all those had low levels of testosterone whichis significant (p value<0.001). The total number of patientswho had triglyceride level of >150, were 80 and all those hadlow levels of testosterone which is significant (p value<0.001).The total number of patients with low testosterone levels inwhom HbA1C was more than 7.5%, were 68. Patients withnormal level of testosterone were 32 in whom HbA1C was6.5-7.5% which is significant (p value<0.001).Conclusion: This study confirmed the high prevalence of lowtestosterone levels in male patients with metabolic syndrome.Multiple associations and predictors of low testosterone levelswere identified by evaluating different demographic, clinicaland other variables.