Cellular immunity status in anaemia in pregnancy.
Article
in En
| IMSEAR
| ID: sea-22308
ABSTRACT
Fifty pregnant women (25 anaemic and 25 non-anaemic) and 20 non pregnant women (10 anaemic and 10 non-anaemic) were studied. All pregnant women delivered full term (37-41 wk) singleton babies. Maternal blood lymphocyte stimulation indices (SI) at 0 and 24 h were lower in anaemic and non-anaemic pregnant women, compared to anaemic and non-anaemic non-pregnant women. This difference was more marked in anaemic pregnant women, as compared to non pregnant anaemic women at 0 and 24 h respectively. The SI of maternal and cord blood lymphocytes were significantly lower in severely anaemic mothers both at 0 and 24 h and in those with maternal serum iron levels below 50 micrograms/dl or maternal per cent transferrin saturation was below 15 per cent. The anaemic mothers and their offspring were found to have significantly lower blastogenic response to PHA added at 24 h indicating depression of T-suppressor cell function.
Full text:
1
Index:
IMSEAR
Main subject:
Phytohemagglutinins
/
Pregnancy Complications, Hematologic
/
Female
/
Humans
/
Pregnancy
/
Lymphocyte Activation
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Fetal Blood
/
Immunity, Cellular
/
Anemia
Language:
En
Year:
1991
Type:
Article