Ten-year follow-up of corneal cross-linking and refractive surface ablation in patients with asymmetric corneal topography
Indian J Ophthalmol
;
2023 Sep; 71(9): 3210-3218
Article
| IMSEAR
| ID: sea-225263
ABSTRACT
Purpose:
Compare the safety and efficacy of wavefront?guided photorefractive keratotomy (PRK) 6 months after cross?linking (CXL) to wavefront?guided PRK alone for refractive correction in patients with bilateral asymmetric corneal topography.Methods:
Prospective randomized clinical trial with 16 patients (32 eyes). CXL with subsequent PRK after 6 months in one eye, and PRK alone was performed in contralateral eyes. The follow?up was 10 years. We analyzed visual outcomes, Scheimpflug topography, and corneal haze evaluation.Results:
Eyes in the PRK group showed better results than in the CXL + PRK group. Mean postoperative CDVA was 0.044 logmar (SD, 0.073) in the PRK group and 0.1 logmar (SD, 0.21) in the CXL + PRK group, the mean sphere was + 0.21 (SD, 0.6) D in the PRK group and 0.87 (SD, 2.3) D in the CXL + PRK group, and mean SE was ?0.35 (SD, 0.65) D in the PRK group and 0.62 (SD, 2.32) D in the CXL + PRK group. In one patient, a steepening of 2.5 D and a thinning of 17 ?m occurred in PRK alone group. Two patients in the CXL + PRK group presented corneal haze. The overall complication rate was 18,75% (haze and ectasia).Conclusion:
Non?simultaneous CXL and PRK procedures yielded good refractive results, but worse than those obtained with PRK alone. Although one patient in the PRK group developed corneal ectasia, the CXL + PRK group had a higher loss of vision lines, indicating less safety
Full text:
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Index:
IMSEAR (South-East Asia)
Journal:
Indian J Ophthalmol
Year:
2023
Type:
Article
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