Functionality of drug efflux pumps in antimonial resistant Leishmania donovani field isolates.

Mandal, Goutam; Sarkar, Avijit; Saha, Piu; Singh, Neeloo; Sundar, Shyam; Chatterjee, Mitali

Mandal, Goutam; Sarkar, Avijit; Saha, Piu; Singh, Neeloo; Sundar, Shyam; Chatterjee, Mitali.

Indian J Biochem Biophys ; 2009 Feb; 46(1): 86-92

Article in En | IMSEAR | ID: sea-26312

Subject(s)

ATP-Binding Cassette Transporters/metabolism; Adenosine Triphosphate/metabolism; Animals; Antimony/pharmacology; Antiprotozoal Agents/pharmacology; Drug Resistance, Multiple; Fluoresceins/metabolism; Humans; Leishmania donovani/drug effects; Leishmania donovani/metabolism; Leishmaniasis, Visceral/drug therapy; Leishmaniasis, Visceral/parasitology; Leishmaniasis, Visceral/physiopathology; Multidrug Resistance-Associated Proteins/antagonists & inhibitors; Multidrug Resistance-Associated Proteins/metabolism; Ofloxacin/pharmacology; Probenecid/pharmacology; Protozoan Proteins/metabolism; Rhodamine 123/metabolism; Verapamil/pharmacology

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Full text: 1 Index: IMSEAR Main subject: Leishmania donovani / Humans / Verapamil / Ofloxacin / Protozoan Proteins / Adenosine Triphosphate / Probenecid / Drug Resistance, Multiple / ATP-Binding Cassette Transporters / Rhodamine 123 Language: En Journal: Indian J Biochem Biophys Year: 2009 Type: Article

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