Antifungal agents and immunomodulators in systemic mycoses.
Indian J Chest Dis Allied Sci
; 2000 Oct-Dec; 42(4): 345-55
Article
in En
| IMSEAR
| ID: sea-30231
ABSTRACT
The rising incidence of fungal infections and the emergence of several fungi as opportunistic pathogens have reawakened interest in chemotherapeutic and prophylactic agents for mycoses. During the past decades significant advances have been made in the development of novel antifungal agents for treatment of systemic mycoses. This brief review presents an update of the available information on polyenes, imidazoles, triazoles, flucytosine, allylamines, echinocandins, nikkomycins, sordarins and immunomodulators. A reference has also been made to the work in antifungals done or in progress at the Central Drug Research Institute (CDRI), Lucknow. Currently, antifungals represent more than 6% of the total world market for anti-infective agents and with 20% annual expansion they are expected to cross the 15 billion US Dollars in value within a decade.
Full text:
1
Index:
IMSEAR
Main subject:
Humans
/
Fungemia
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Immunologic Factors
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Mycoses
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Antifungal Agents
Language:
En
Journal:
Indian J Chest Dis Allied Sci
Year:
2000
Type:
Article