Motility and drug susceptibility of Angiostrongylus cantonensis developing from gamma-irradiated first-stage larvae.
Southeast Asian J Trop Med Public Health
; 1987 Dec; 18(4): 547-51
Article
in En
| IMSEAR
| ID: sea-32834
ABSTRACT
The effects of neuropharmacological agents on the motility of irradiated and non-irradiated Angiostrongylus cantonensis adult females were studied. GABA induced complete paralysis in non-irradiated and 5,000 R-irradiated worms, but caused only slight paralysis on 10,000 R-irradiated worms. The paralytic effect of GABA was antagonised by picrotoxin. The reason for low susceptibility of heavily irradiated worms to GABA is not known. There was no difference in susceptibility of non-irradiated and irradiated worms to other neuropharmacological agents including eserine, phenylephrine and dibenamine.
Full text:
1
Index:
IMSEAR
Main subject:
Phenylephrine
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Physostigmine
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Picrotoxin
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Rats
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Rats, Inbred Strains
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Autonomic Agents
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Strychnine
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Female
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Male
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Convulsants
Language:
En
Journal:
Southeast Asian J Trop Med Public Health
Year:
1987
Type:
Article