Co-existence of HIV-1 subtypes B' and E infections among Thai injecting drug users.
Asian Pac J Allergy Immunol
; 2002 Mar; 20(1): 29-35
Article
in En
| IMSEAR
| ID: sea-37111
ABSTRACT
Subtypes B' and E are the two major subtypes of HIV-1 among injecting drug users (IDU) in Thailand. However, there are not many reports on subtype distribution during the early epidemic. Random blood specimens collected during 1994-2000 from 3,286 IDU at the Thanyarak Hospital were tested for HIV antibody and subtyped by using peptide binding enzyme immunoassay. The prevalence rate of HIV infection was 36.8%. All HIV-seropositive IDU were ascertained for "year of first HIV seropositivity" from their medical records. Of 1,512 HIV-seropositive samples, 1,408 (93.1%) were typeable. During 1987-1988, the proportion of subtype B' was as high as 80% but decreased rapidly to 27.6% during 1999-2000. At the same time, the proportions of subtype E increased correspondingly (Chi-square test for the trend, p < 0.05). The relatively high proportion of subtype E among IDU since an early stage of the epidemic suggests early co-existence of both subtypes and needs further investigation.
Full text:
1
Index:
IMSEAR
Main subject:
Opium
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Thailand
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Female
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Humans
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Male
/
HIV Infections
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Substance Abuse, Intravenous
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Sex Factors
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Prevalence
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Adolescent
Type of study:
Prevalence_studies
Country/Region as subject:
Asia
Language:
En
Journal:
Asian Pac J Allergy Immunol
Year:
2002
Type:
Article