Growth pattern of childhood thyrotoxicosis: longitudinal follow-up to final height.
Article
in En
| IMSEAR
| ID: sea-41409
ABSTRACT
OBJECTIVE:
To study the growth pattern of children affected with thyrotoxicosis. MATERIAL ANDMETHOD:
A retrospective study of growth data of 40 patients with thyrotoxicosis diagnosed at prepuberty or at early puberty was conducted. All patients were evaluated for height and weight every 3-6 months. Height and weight were transformed to standard deviation score (SDS) to account for differences of age and sex.RESULTS:
At the time of diagnosis, the patients were slightly underweight for height (weight SDS -0.27 +/- 1.24, height SDS -0.06 +/- 1.26). After 1 year of treatment, the average weight gain of the patients was 4.9 +/- 3.1 kg, resulting in becoming relatively overweight for height (weight SDS +0. 32 +/- 1.42, height SDS +0.02 +/- 1.32). At the time of reaching their final height, the patients had an appropriate weight for height (weight SDS +0.06 +/- 0.21, height SDS -0.04 +/- 1.01). The average final height SDS of the patients was -0.04 +/- 1.01. This was at the average of the general population, but was +0.57 +/- 0.48 SDS or +2.85 +/- 1.0 cm greater than their target height (p < 0.01).CONCLUSION:
Growth of patients with thyrotoxicosis showed the same pattern as in the general population. The final height of thyrotoxicosis patients was averagely +0.57 SDS or +2.85 cm greater than their genetic potential. This could be from the result of secular trend in the general population rather than being the effect of thyrotoxicosis.
Full text:
1
Index:
IMSEAR
Main subject:
Body Height
/
Thyrotoxicosis
/
Female
/
Humans
/
Male
/
Child
/
Follow-Up Studies
/
Growth
Type of study:
Observational_studies
/
Prognostic_studies
Language:
En
Year:
2006
Type:
Article