High CD4+ T-cells percentage and/or low viral load are predictors of 1-5 years survival in HIV-1 vertically infected Thai children.
Article
in En
| IMSEAR
| ID: sea-44552
ABSTRACT
OBJECTIVE:
Enrolling pediatric HIV children into the clinical trial of when to initiate antiretroviral therapy is a crucial ethical issue. CD4+ T-cells percentage and/or viral load were able to identify potential cases of survival through 5 years of age.METHOD:
HIV infected cohort from 1992 to 1994 from Children's and Siriraj Hospitals were followed from 1 through 5 years of age. The outcome was survival or death. The predictors were CD4 percentage and viral load (without age and clinical status adjustment).RESULT:
16 of 35 (45.71%) of the cohort survived through 5 years of age. The probability of survival increased to almost 100 per cent either with CD4+ T-cells percentage of over 22 or viral load of less than 500,000.
Full text:
1
Index:
IMSEAR
Main subject:
Thailand
/
Severity of Illness Index
/
Female
/
Humans
/
Male
/
Pregnancy
/
Biomarkers
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CD4-Positive T-Lymphocytes
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CD4 Antigens
/
HIV Infections
Type of study:
Diagnostic_studies
/
Prognostic_studies
Country/Region as subject:
Asia
Language:
En
Year:
2002
Type:
Article