Role of chelates in treatment of cancer.
Indian J Cancer
; 2007 Apr-Jun; 44(2): 62-71
Article
in En
| IMSEAR
| ID: sea-50641
ABSTRACT
Chelates are used in cancer as cytotoxic agent, as radioactive agent in imaging studies and in radioimmunotherapy. Various chelates based on ruthenium, copper, zinc organocobalt, gold, platinum, palladium, cobalt, nickel and iron are reported as cytotoxic agent. Monoclonal antibodies labeled with radioactive metals such as yttrium-90, indium-111 and iodine-131 are used in radioimmunotherapy. This review is an attempt to compile the use of chelates as cytotoxic drugs and in radioimmunotherapy.
Full text:
1
Index:
IMSEAR
Main subject:
Radioisotopes
/
Rats
/
Humans
/
Chelation Therapy
/
Chelating Agents
/
Treatment Outcome
/
Radioimmunotherapy
/
Cytotoxins
/
Cell Growth Processes
/
Drug Therapy
Language:
En
Journal:
Indian J Cancer
Year:
2007
Type:
Article