Cytological study of copper in oral submucous fibrosis.
Article
in English
| IMSEAR
| ID: sea-51870
ABSTRACT
BACKGROUND:
Habitual arecanut chewing is associated with Oral Submucous Fibrosis (OSF). High copper content in arecanut plays a vital role in pathogenesis of OSF. This study evaluates the copper-staining pattern of buccal epithelial cells in oral cytological smears of non-chewers, chewers, and OSF. MATERIALS &METHODS:
Alcohol fixed buccal epithelial smears of 10 histopathologically confirmed cases of OSF, 10 chewers without lesion, and 5 nonchewers were stained with modified Rhodamine technique and studied under the light microscope. Buccal epithelial smears of non-chewers dipped in copper sulphate solution were used as known positive for copper.RESULT:
Copper appeared as shades of palered within the cytoplasm of chewers and did not show any stain in non-chewers. Intense red stain was seen in OSF smears as dark granules within the cytoplasm.CONCLUSION:
Intense staining of copper in OSF buccal smears, than in the chewers supports the role of copper in the pathogenesis of OSF.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Oral Submucous Fibrosis
/
Areca
/
Rhodamines
/
Humans
/
Copper
/
Cytoplasm
/
Epithelial Cells
/
Fluorescent Dyes
/
Mouth Mucosa
Language:
English
Year:
2004
Type:
Article
Similar
MEDLINE
...
LILACS
LIS