Tuberous sclerosis with portal vein thrombosis, protein C and S deficiency.
Indian J Dermatol Venereol Leprol
; 2007 Nov-Dec; 73(6): 412-4
Article
in En
| IMSEAR
| ID: sea-53003
ABSTRACT
A 29-year-old lady with a bad obstetric history and portal vein thrombosis, presented to the Skin OPD for facial lesions. On examination, angiofibromas on face, shagreen patch and periungual fibromas were observed. She also had dental pits and a retinal hamartoma. Investigations revealed hamartomas in the brain and kidney. Hematological work-up showed protein C and S deficiency with Factor V Leiden positivity. Except for the cutaneous symptoms, the patient did not have any clinical manifestations in other organs affected by tuberous sclerosis. A similar association of tuberous sclerosis with protein C deficiency has been reported in only one case in literature.
Full text:
1
Index:
IMSEAR
Main subject:
Portal Vein
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Retinal Diseases
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Thrombosis
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Tuberous Sclerosis
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Dental Fissures
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Brain Diseases
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Female
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Humans
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Facial Neoplasms
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Angiofibroma
Language:
En
Journal:
Indian J Dermatol Venereol Leprol
Year:
2007
Type:
Article