Impact of feeding ethanolic extracts of Achyranthes aspera Linn. on reproductive functions in male rats.
Indian J Exp Biol
; 2002 Nov; 40(11): 1307-9
Article
in En
| IMSEAR
| ID: sea-55673
ABSTRACT
Feeding 50% ethanolic extract of A. aspera to male rats resulted in reduced sperm counts, weight of epididymis, serum level of testosterone and testicular activity of 3beta-hydroxysteroid dehydrogenase, while motility of the sperm and activity of the HMG CoA reductase were not affected. Cholesterol level in the testis, incorporation of labelled acetate into cholesterol, 17-ketosteroids in urine and hepatic and fecal bile acids were increased. The results suggest that ethanolic extract of A. aspera caused reproductive toxicity in male rats and the action may be by suppressing the synthesis of androgen.
Full text:
1
Index:
IMSEAR
Main subject:
Organ Size
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Rats
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Seminal Vesicles
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Solvents
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Sperm Count
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Sperm Motility
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Testis
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Testosterone
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Male
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Plant Extracts
Language:
En
Journal:
Indian J Exp Biol
Year:
2002
Type:
Article