In vivo suppression of pituitary and circulatory follicle stimulating hormone by human seminal plasma inhibin.
Indian J Exp Biol
; 1991 Apr; 29(4): 310-4
Article
in En
| IMSEAR
| ID: sea-57951
ABSTRACT
Human seminal plasma inhibin (HSPI), of prostatic origin, has been shown to bring about a dose dependent suppression in pituitary and circulatory FSH concentrations in intact rats. No significant changes in LH levels either in pituitary or in circulation were observed at the doses used. This has further been substantiated by an immunocytochemical staining. A marked reduction in staining intensity for FSH was observed in the pituitary of inhibin treated rats as compared to the controls. None of the purified inhibin peptides from other sources have so far been reported to act on pituitary FSH in vivo. This study thus, for the first time demonstrates an in vivo effect of inhibin (HSPI) on pituitary FSH concentration and secretion.
Full text:
1
Index:
IMSEAR
Main subject:
Pituitary Gland
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Rats
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Rats, Inbred Strains
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Humans
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Male
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Follicle Stimulating Hormone
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Inhibins
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Animals
Language:
En
Journal:
Indian J Exp Biol
Year:
1991
Type:
Article