Xanthine oxidase, superoxide dismutase, catalase and lipid peroxidation in Mastomys natalensis: effect of Dipetalonema viteae infection.
Indian J Exp Biol
;
1989 Dec; 27(12): 1067-70
Article
in English
| IMSEAR
| ID: sea-63295
ABSTRACT
Status of xanthine oxidase, superoxide dismutase, catalase and lipid peroxidation, the enzymes metabolizing reactive oxygen intermediates in liver, lungs and spleen of M. natalensis during D. viteae infection was investigated. Xanthine oxidase and lipid peroxidation exhibited stimulation, while superoxide dismutase and catalase showed depression in liver and spleen of the infected animals. The filarial infection therefore appears to create O2 toxicity in these tissues. Lungs, on the other hand was found safe as it possessed elevated xanthine oxidase, superoxide dismutase and catalase. Lipid peroxidation in lungs operated below the control level. The impact of these changes in the establishment and development of the infection has been discussed.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Superoxide Dismutase
/
Xanthine Oxidase
/
Lipid Peroxidation
/
Catalase
/
Analysis of Variance
/
Dipetalonema Infections
/
Filariasis
/
Animals
/
Muridae
Language:
English
Journal:
Indian J Exp Biol
Year:
1989
Type:
Article
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