Role of redchilli (Capsaicin) in the formation of colonic carcinoma.

Chitra, S; Viswanathan, P; Nalini, N; Sabitha, K; Menon, V P

Chitra, S; Viswanathan, P; Nalini, N; Sabitha, K; Menon, V P.

Indian J Pathol Microbiol ; 1997 Jan; 40(1): 21-5

Article in En | IMSEAR | ID: sea-75599

ABSTRACT

ABSTRACT

The effect of feeding redchilli (Capsaicin) powder on the histopathological changes occurring in the colonic mucosa was studied in rats. These animals were compared with those treated with a colonic carcinogen 1,2-dimethylhydrazine (DMH). Animals fed with redchilli, dimethylhydrazine, dimethylhydrazine plus redchilli powder showed polyp and dysplasia, malignant tumour and malignant tumour with transitional area of dysplasia.

Subject(s)

1,2-Dimethylhydrazine; Animals; Carcinoma/etiology; Colonic Diseases/etiology; Colonic Neoplasms/etiology; Dimethylhydrazines/adverse effects; Male; Rats; Rats, Sprague-Dawley; Spices/adverse effects

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Full text: 1 Index: IMSEAR Main subject: Rats / Male / Carcinoma / Spices / Rats, Sprague-Dawley / Colonic Diseases / Colonic Neoplasms / 1,2-Dimethylhydrazine / Dimethylhydrazines / Animals Language: En Journal: Indian J Pathol Microbiol Year: 1997 Type: Article

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