Cytogenetic studies in a population suspected to have chromosomal abnormalities.
Indian J Pediatr
; 1990 Mar-Apr; 57(2): 235-43
Article
in En
| IMSEAR
| ID: sea-83795
ABSTRACT
The present study describes the cytogenetic findings in cases suspected with chromosomal abnormalities, in cases of mental retardation, multiple congenital malformations, clinical features of Down's syndrome, Klinefelter's syndrome, Turner's syndrome, ambiguous sex, sterility, amenorrhea and history of repeated spontaneous abortions in couples. Cytogenetic studies were done in 144 of the total 205 cases. In all, 57 (39.58%) were shown to have chromosomal abnormality and of these, 34 cases (25.7%) were Down's syndrome. Sex chromosome abnormality was found in 19 cases (13.2%). The results confirm the significant contribution of chromosomal abnormalities in the genesis of mental retardation, and abnormal sexual development.
Full text:
1
Index:
IMSEAR
Main subject:
Female
/
Humans
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Male
/
Chromosome Aberrations
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Chromosome Banding
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Chromosome Disorders
/
Karyotyping
Language:
En
Journal:
Indian J Pediatr
Year:
1990
Type:
Article