Respiratory failure in acute intermittent porphyria.
Article
in En
| IMSEAR
| ID: sea-95355
ABSTRACT
We report two patients of acute intermittent porphyria (AIP) who presented with acute respiratory failure. Only one such previous report could be found. Occasionally, neuropathy may be the presenting feature in AIP which may progress to respiratory embarrassment. The cause of this neuropathy has been hypothesized to be direct neurotoxicity of delta-ALA by interaction with GABA receptor, altered tryptophan metabolism and may be heme depletion in nerve cells.
Full text:
1
Index:
IMSEAR
Main subject:
Respiratory Distress Syndrome
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Female
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Humans
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Male
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Intermittent Positive-Pressure Ventilation
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Porphyria, Acute Intermittent
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Fatal Outcome
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Adult
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Intensive Care Units
Language:
En
Year:
2002
Type:
Article