Advances in enzymatic production of L-homophenylalanine / 生物工程学报
Chinese Journal of Biotechnology
; (12): 3111-3124, 2023.
Article
in Zh
| WPRIM
| ID: wpr-1007948
Responsible library:
WPRO
ABSTRACT
L-homophenylalanine (L-HPA) is an important non-natural amino acid that has been used as a key intermediate for the synthesis of Puli drugs for the treatment of hypertension. At present, L-HPA is synthesized using chemical methods, which has the disadvantages of expensive raw materials, tedious steps and serious pollution. Therefore, researchers have conducted in-depth research on the enzymatic production of L-HPA. This review summarizes the research progress on the enzymatic synthesis of L-HPA, including the dehydrogenase process, the transaminase process, the hydantoinase process, and the decarboxylase process, with the hope to facilitate the industrial production of L-HPA.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Protein Biosynthesis
/
Environmental Pollution
/
Amino Acids
/
Industry
Language:
Zh
Journal:
Chinese Journal of Biotechnology
Year:
2023
Type:
Article