Research progress in vaccines of SARS-CoV-2 / 细胞与分子免疫学杂志
Chinese Journal of Cellular and Molecular Immunology
; (12): 946-951, 2023.
Article
in Zh
| WPRIM
| ID: wpr-1009452
Responsible library:
WPRO
ABSTRACT
Since the outbreak of corona virus disease 2019 (COVID-19), viral strains have mutated and evolved. Vaccine research is the most direct and effective way to control COVID-19. According to different production mechanisms, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines included inactivated virus vaccine, live attenuated vaccine, mRNA vaccine, DNA vaccine, viral vector vaccine, virus-like particle vaccine and protein subunit vaccine. Among them, viral protein subunit vaccine has a wide application prospect due to its high safety and effectiveness. Viral nucleocapsid protein has high immunogenicity and low variability which could be a new direction for vaccine production. We summarized the current development of vaccine research by reviewing the current progress, vaccine safety and vaccine immune efficiency. It is hoped that the proposed possible development strategies could provide a reference for epidemic prevention work in future.
Full text:
1
Index:
WPRIM
Main subject:
Vaccines, DNA
/
Nucleocapsid Proteins
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Protein Subunits
/
SARS-CoV-2
/
COVID-19
Limits:
Humans
Language:
Zh
Journal:
Chinese Journal of Cellular and Molecular Immunology
Year:
2023
Type:
Article