Proapoptotic protein Bim regulates the suppressive function of Treg cells / 浙江大学学报(英文版)(B辑:生物医学和生物技术)
Journal of Zhejiang University. Science. B
; (12): 1180-1184, 2023.
Article
in En
| WPRIM
| ID: wpr-1010593
Responsible library:
WPRO
ABSTRACT
Regulatory T (Treg) cells are a special immunosuppressive subset of cluster of differentiation 4-positive (CD4+)-T lymphocytes and play a pivotal role in the establishment of immune homeostasis in vivo (Zhang et al., 2021). The transcription factor forkhead box protein P3 (Foxp3) is the master marker of Treg cells, which is highly expressed in Treg cells and is also essential for their suppressive function (Hori et al., 2003). In addition to Foxp3, other regulators of Treg cells have been discovered (Wu et al., 2017, 2022; Wu and Sun, 2023a, 2023b); however, a deeper understanding of the regulation of these cells is required.
Full text:
1
Index:
WPRIM
Main subject:
Gene Expression Regulation
/
T-Lymphocytes, Regulatory
/
Forkhead Transcription Factors
Language:
En
Journal:
Journal of Zhejiang University. Science. B
Year:
2023
Type:
Article