Detection of Anti-Lua in an Unexpected Antibody Screening Test: A Case Report and Literature Review / 대한수혈학회지
Korean Journal of Blood Transfusion
; : 169-172, 2012.
Article
in Ko
| WPRIM
| ID: wpr-101146
Responsible library:
WPRO
ABSTRACT
Lutheran a antigen (Lua) is detected in 6 to 8% of Caucasians and Africans. In Korean and other Asian populations, it is very rare or nearly absent. Therefore, although Lua has a considerable immunizing capacity, sensitization to Lua is a rare event. Here we report on a rare case of anti-Lua in a 70 year-old female patient with Lu (a-/b+) phenotype and review the relevant literature. Due to the paucity of Lua positive panel cells in antibody screening and identification tests, detection of this rare antibody to Lua antigen is not feasible. Therefore, we should keep in mind the possibility of the misleading false negative result in detection of antibody to this low incidence antigen.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Phenotype
/
Mass Screening
/
Incidence
/
Protestantism
/
Asian People
/
Lutheran Blood-Group System
Type of study:
Diagnostic_studies
/
Incidence_studies
/
Prognostic_studies
/
Screening_studies
Limits:
Female
/
Humans
Language:
Ko
Journal:
Korean Journal of Blood Transfusion
Year:
2012
Type:
Article