Oxymatrine regulates autophagy through AMPK/mTOR pathway to inhibit OGD/R-induced damage in astrocytes / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 2331-2338, 2023.
Article
in Zh
| WPRIM
| ID: wpr-1013668
Responsible library:
WPRO
ABSTRACT
Aim To investigate the role of autophagy regulated by the AMPK/mTOR pathway in the prevention of oxygen-glucose deprivation/reperfusion injury ( OGD/R) in astrocytes using oxymatrine ( OMT ) . Methods The isolated and purified astrocytes ( AS) were randomly divided into control group ( CON group), OGD/R group and OGD/R + OMT group (0. 1, 0. 2, 0. 4 mmol · L
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WPRIM
Language:
Zh
Journal:
Chinese Pharmacological Bulletin
Year:
2023
Type:
Article