Effect of a novel phosphodiesterase type 5 inhibitor, CPD1, on carbon tetrachloride-induced liver fibrosis in mice

Wen-Bin FENG; Jian-Qin YANG; Xin-Hui CHEN; Zhong-Lian XIE; Ying-Ying ZHANG; Ying-Xi CHEN; Zi-Jian ZHAO; Yun-Ping MU; Fang-Hong LI

Effect of a novel phosphodiesterase type 5 inhibitor, CPD1, on carbon tetrachloride-induced liver fibrosis in mice / 中国药理学通报

Wen-Bin FENG; Jian-Qin YANG; Xin-Hui CHEN; Zhong-Lian XIE; Ying-Ying ZHANG; Ying-Xi CHEN; Zi-Jian ZHAO; Yun-Ping MU; Fang-Hong LI.

Chinese Pharmacological Bulletin ; (12): 470-476, 2023.

Article in Zh | WPRIM | ID: wpr-1013838

Responsible library: WPRO

ABSTRACT

ABSTRACT

Aim To investigate the effects of CPD1, a novel phosphodiesterase 5 inhibitor, on liver pathological phenotype and hepatic stellate cells (HSCs) activation in hepatic fibrosis model mice caused by carbon tetrachloride ( CCl

Key words

activation; carbon tet-rachloride; CPD1; hepatic stellate cells; liver fibrosis; phosphodiesterase type 5 inhibitors

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Full text: 1 Index: WPRIM Language: Zh Journal: Chinese Pharmacological Bulletin Year: 2023 Type: Article

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Full text: 1 Index: WPRIM Language: Zh Journal: Chinese Pharmacological Bulletin Year: 2023 Type: Article