Progress on omalizumab treatment for refractory asthma in children / 国际儿科学杂志
International Journal of Pediatrics
; (6): 619-623, 2023.
Article
in Zh
| WPRIM
| ID: wpr-1017673
Responsible library:
WPRO
ABSTRACT
The incidence of refractory asthma in children is increasing year by year, bringing a heavy disease burden to families and society.As the immunological, pathophysiological and neurological mechanisms of asthma be elucidated, typeⅠallergic reactions mediated by the immunoglobulin E play an important role in the development of asthma.Omalizumab, targeting IgE, is using in clinical.This paper reviews the mechanism of action and clinical efficacy of omalizumab based on a review of the pathogenesis of refractory asthma, with the aim of guiding the individualized treatment of children with refractory asthma, improving the overall control rate.
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WPRIM
Language:
Zh
Journal:
International Journal of Pediatrics
Year:
2023
Type:
Article