The pathogenesis of diabetes retinopathy:progress in miRNAs / 眼科新进展
Recent Advances in Ophthalmology
; (6): 244-247, 2024.
Article
in Zh
| WPRIM
| ID: wpr-1022751
Responsible library:
WPRO
ABSTRACT
Diabetic retinopathy,a main microvascular complication of diabetes,remains the leading cause of blindness in the working-age population,but its specific pathogenesis has not been fully elucidated.microRNAs(miRNAs)are small non-coding RNAs,acting as post-transcriptional regulators of gene expression.Its aberrant expression plays a key role in modulating pathological processes associated to many diseases.Studies confirmed the role of miRNAs in the regulation of oxidative stress,inflammation,cell death and angiogenesis which influences the development of DR.This review focuses on the role of miRNAs in DR,which may provide a reference basis for diagnosis,prognosis and therapeutics.
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WPRIM
Language:
Zh
Journal:
Recent Advances in Ophthalmology
Year:
2024
Type:
Article