Meta-analysis on failure mode and effect analysis for the prevention of ICU-acquired infection / 中国感染控制杂志

ABSTRACT

Objective To systematically evaluate the effectiveness of failure mode and effect analysis(FMEA)in the prevention of intensive care unit(ICU)-acquired infection.Methods Two researchers independently searched relevant literatures from foreign and Chinese databases,with a search deadline of July 15,2022.Independent screening of literatures,extraction of data and evaluation on overall quality were performed according to inclusion and exclusion criteria.RevMan 5.4 software was used to conduct Meta-analysis on the preventive effect of the in-cluded literatures.Results A total of 19 literatures were included in analysis.Meta-analysis results showed that ap-plication of FMEA method reduced the incidences of ventilator-associated pneumonia(OR=0.40,95％CI[0.31-0.51],P＜0.01),catheter-associated urinary tract infection(OR=0.29,95％CI[0.17-0.51],P＜0.01),cen-tral line-associated bloodstream infection(OR=0.28,95％CI[0.18-0.46],P＜0.01),and multidrug-resistant organism infection(OR=0.46,95％CI[0.37-0.58],P＜0.01)in ICU patients,as well as incidence of health-care-associated infection(HAI)in ICU(OR=0.46,95％CI[0.37-0.59],P＜0.01),and significantly improved the satisfaction of ICU patients and their families(OR=2.34,95％CI[1.72-3.17],P＜0.01).Conclusion FMEA can effectively prevent ICU-acquired infection and improve the quality of HAI management.