Bioelectromagnetic dosimetric study of human blood-brain barrier opening induced by electromagnetic pulse / 中国医学物理学杂志
Chinese Journal of Medical Physics
; (6): 241-246, 2024.
Article
in Zh
| WPRIM
| ID: wpr-1026217
Responsible library:
WPRO
ABSTRACT
Objective To analyze the bioelectromagnetic dose of human blood-brain barrier opening induced by electromagnetic pulse.Methods A typical exposure platform was used to establish an environment for human brain dosimetric study.The bioelectromagnetic dose was evaluated with electromagnetic simulation method using a 3D digital human model.Results The electric field at the centre of the head reached a peak of 1.49 kV/m,and there was a decrease of 41.6 dB from the excitation field.The maximum electric field amplitude on the surface of the nose tip was 1795 kV/m.The head had an average absorption rate of 4.16×10-8 J/kg under one pulse,while under extreme conditions with a repetition frequency of 1000 s-1,the average specific absorption rate of the head was 4.16×10-5 W/kg.Conclusion Local high-intensity electric fields pose significant safety risks in clinical application,and it is necessary to study the means of inhibiting local high-intensity electric field in combination with the dose-effect relationship of blood-brain barrier opening.The human brain bioelectromagnetic doses provided by the study can be used to evaluate the clinical efficacy.
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Medical Physics
Year:
2024
Type:
Article