Frame-based stereotactic biopsy in diagnosis of small solid tumor in the suprasellar region / 中华神经医学杂志

ABSTRACT

Objective:To investigate the diagnostic value of frame stereotactic biopsy in patients with small solid tumors in the suprasellar region.Methods:From April 2018 to December 2020, 42 patients with solid tumors in the suprasellar region were selected in our hospital. All patients underwent frame stereotactic biopsy under multimodal image guidance. The imaging characteristics, histological and pathological diagnosis rate, and incidence of biopsy complications of these patients were analyzedResults:(1) CT examination showed that the suprasellar cistern lesions were lumpy and well defined; 41 had high/slightly high density and 1 had calcification. MRI examination showed that the lesions were also lumpy and the signal was relatively uniform; enhanced images showed that 3 patients had "salt and pepper sign"; Magnetic Resonance Spectrum showed that 2 had typical huge Lip composite peak. (2) All 42 patients underwent frame stereotactic biopsy successfully, and 35 patients (83.3%) were pathologically diagnosed, including 24 with germinoma (GE), one with embryonal carcinoma, 6 with Langerhans histiocytosis (LCH), 2 with hair-cell astrocytoma, and 2 with diffuse large B-cell lymphoma. Postoperative head CT showed that two were with micro-hemorrhage in the operation area, and the rest showed no signs of hemorrhage. No significant changes were observed in the clinical manifestations before and after surgery.Conclusion:Frame-based stereotactic biopsy is safe and reliable, with few surgical complications and high diagnosis rate in small solid tumors in the suprasellar region.