Recent advance in encephalitis associated with anti-Kelch-like protein 11 antibody / 中华神经医学杂志

ABSTRACT

Anti-kelch-like protein 11 (KLHL11) antibody associated encephalitis is a type of paraneoplastic encephalitis associated with testicular seminoma, with marginal encephalitis symptoms appearing in a few cases. Vertigo, hearing loss, and tinnitus are common and unique clinical symptoms in patients with KLHL11 antibody associated encephalitis. Treatment options include immunotherapy, symptomatic therapy, and antitumor therapy for patients with concomitant tumors. In order to improve the understanding of this disease among clinical medical workers, the authors review the epidemiological characteristics, pathogenesis and clinical manifestations of anti-KLHL11 antibody associated encephalitis as follows.