Immunoglobulin G4-Related Disease Mimicking Unresectable Gallbladder Cancer
Gut and Liver
; : 616-620, 2013.
Article
in En
| WPRIM
| ID: wpr-103732
Responsible library:
WPRO
ABSTRACT
Immunoglobulin G4 (IgG4)-related disease is a novel disease entity that can involve diverse organs, causing specific diseases, including autoimmune pancreatitis, sclerosing cholangitis, cholecystitis, inflammatory aortic aneurysm, and inflammatory pseudotumor. IgG4-related disease is characterized by elevated serum IgG4 concentrations, abundant IgG4 lymphoplasmacytic infiltration, and dramatic steroid responses. It is clinically important to differentiate this rare disease from primary sclerosing cholangitis and cholangiocarcinoma, because the treatment and prognosis of these two diseases are completely different. However, the preoperative diagnosis is challenging, and the disease is frequently misdiagnosed. If the serum level of IgG4 is within the normal range, the diagnosis of IgG4-related disease is more difficult. This article reports on a 59-year-old man with IgG4-related disease mimicking unresectable gallbladder cancer with normal serum IgG4 concentrations.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Aortic Aneurysm
/
Pancreatitis
/
Prognosis
/
Reference Values
/
Immunoglobulin G
/
Immunoglobulins
/
Cholangitis, Sclerosing
/
Cholecystitis
/
Cholangiocarcinoma
/
Rare Diseases
Type of study:
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Gut and Liver
Year:
2013
Type:
Article