The feasibleness study of forecasting the prognostic of sick person acute ischemic stroke by intravenous thrombolysis based on multi-phase CTA / 中风与神经疾病杂志

ABSTRACT

@#Evaluate the feasibleness of forecast the prognostic of sick person acute ischemic stroke Intravenous thrombolysis based on multi-phase CT angiography（mCTA）united with medical message. MethodsThe sufferer acute ischemic stroke accomplished mCTA scan were choose. The multi-phase ASPECTS collateral circulation，blood glucose results red blood cell distribution width（RDW）and neutrophil to lymphocyte ratio（NLR）were record. Pursuant to the modified Rankin Scale（mRS）as the criterion，90 daytime after therapy，sufferer mRS score≤2 were specified as set A（n=18），and sufferer mRS score≥3 were specified as set B（n=33）. The information with statistics discrepancies in univariate analysis were contained in binary Logistics regression analysis. The standalone risk elements for forecast the prognostic of sick person acute ischemic stroke were sifted out and the prognostic modeling was effected. The ROC curvature of all the variable with statistics meaning and the binary Logistics regression analysis was used to assess the diagnosis effectivity，Delong test was used to evaluate the discrepancies in between the ROC curvature. ResultsThe blood glucose results，RDW and NLR of set A were higher than those of set B，and the multi-phase score of set A was lower Compare of set B（P<0.05）. Binary Logistics regression analysis showed multi-phase score and NLR were standalone risk factor for 90 daytime prognostic of sick person acute ischemic stroke. The prediction model was logit（P）=-4.877+aspects score×-0.624+NLR×When the threshhold was 0.5288，the sensitivities and specificity were 77.8% and 93.9%，respectively. ConclusionAspects score and NLR are independent risk factors for predicting 90 daytime prognosis of patients with AIS. multi-phase CTA combined with laboratory examination can forecast the prognostic of sick person acute ischemic stroke and bestow precise forecast information for clinical sick person acute ischemic stroke.