Study on the predictive value of island sign and coagulation function in hematoma enlargement of hypertensive intracerebral hemorrhage / 中风与神经疾病杂志

ABSTRACT

@#Objective　To explore the relationship between island sign,coagulation function and hematoma enlargement of HICH,and to study their predictive value for hematoma enlargement.Methods　We selected HICH patients in the Department of Neurosurgery of Wuhan Puren Hospital from January 2019 to January 2021 as the research objects.According to whether there is an enlarged hematoma,the patients were divided into an enlarged hematoma group and an unexpanded hematoma group.We compared the baseline data of the two groups and used a multivariate logistics regression analysis method to analyze independent risk factors for hematoma enlargement.We used ROC curve and AUC to analyze and compare the predictive value of island sign and coagulation function for hematoma enlargement of HICH.Results　Whether the hematoma breaks into the ventricle,island sign,GCS score,PT,INR,hematoma volume,blood sugar level is related to hematoma enlargement of HICH (P＜0.05).Among them,the island sign,GCS score,PT,and whether the hematoma breaks into the ventricle are independent risk factors for hematoma enlargement of HICH (P＜0.05).The AUC of island and coagulation function＞AUC of individual island sign and AUC of individual coagulation function (P＜0.05).Conclusion　Compared with the island sign or PT alone,the island sign combined with PT has a better predictive value for hematoma enlargement of HICH.