Therapeutic Response for Functional Abdominal Pain in Children with Occult Constipation: Laxatives versus Prokinetic Drugs
Journal of Korean Medical Science
; : 102-107, 2017.
Article
in En
| WPRIM
| ID: wpr-104374
Responsible library:
WPRO
ABSTRACT
The relationship between functional abdominal pain (FAP) and occult constipation (OC) in children who did not meet the Rome III criteria for constipation has rarely been reported. This study aimed to estimate the prevalence of OC in patients with FAP and to compare the effectiveness of prokinetic drugs and laxatives for FAP and OC. Pediatric outpatients (n = 212; aged 4–15 years) who satisfied the Rome III criteria for childhood FAP were divided into 2 groups based on Leech scores group 1 < 8; group 2 ≥ 8. Group 2 received either prokinetic drugs or laxatives and pain severity was assessed after 2 weeks, 1 month, and 3 months. A total 52.4% (111/212) of patients had OC in this study. More patients who received laxatives had reduced pain scores compared with those who received prokinetic drugs. Those treated with laxatives in group 2 had a better response than those treated with prokinetic drugs throughout the study period (P < 0.001, P < 0.001, and P = 0.002 after 2 weeks, 1 month, and 3 months, respectively). OC was frequently encountered in children with FAP. Laxatives can be more effective than prokinetic drugs for relieving symptoms of FAP in children with a Leech score ≥ 8 and suspected OC.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Outpatients
/
Pediatrics
/
Abdominal Pain
/
Prevalence
/
Constipation
/
Laxatives
/
Gastrointestinal Diseases
Type of study:
Prevalence_studies
Limits:
Child
/
Humans
Language:
En
Journal:
Journal of Korean Medical Science
Year:
2017
Type:
Article