Sensitization to component antigens in acute idiopathic urticaria in children
Allergy, Asthma & Respiratory Disease
; : 331-335, 2017.
Article
in Ko
| WPRIM
| ID: wpr-114707
Responsible library:
WPRO
ABSTRACT
PURPOSE:
The aim of this study was to evaluate hidden allergens of acute idiopathic urticaria (AIU) in childhood by using the component-resolved diagnostics (CRD).METHODS:
We applied CRD using pathogenesis-related protein family number 10 (PR-10) and nonspecific lipid transfer proteins (nsLTP).RESULTS:
Twenty-two of the 74 AIU children (29.7%) were found to be positive on CRD. Ten children were positive to nMal d 1 for apple (value range, 1.10–40.59), 6 to rConr a 1 for hazelnut (1.53–11.97), 4 to rPru p 1 for peach (1.32–11.83). 6 to rAra h 8 for peanut (1.20–8.12), 6 to nAct d 8 for kiwi (0.85–3.32), 4 to rBet v 1 for birch (2.49–54.28), and 3 to rAln g 1 for alder (2.32–5.74). Six children were positive to nPru p 3 for peach (1.45–18.77), 4 to rCor a 8 for hazelnut (2.56–9.19), 2 to nArt v 3 for mugwort (3.40–7.42), and 3 to rBet v2 to profilin of birch (2.56–17.46). Ten children with AIU were positive to multiple component proteins. For hazelnut, 5 children were positive to PR-10 (rConr a 1) and nsLTP (rConr a 1). For peach, 3 children were positive to PR-10 (rPru p 1) and nsLTP (nPru p 3).CONCLUSION:
IgE sensitization to PR-10 or nsLTP may be allergen components for AIU in childhood.Key words
Full text:
1
Index:
WPRIM
Main subject:
Arachis
/
Urticaria
/
Immunoglobulin E
/
Allergens
/
Artemisia
/
Alnus
/
Betula
/
Corylus
/
Diagnosis
/
Profilins
Type of study:
Diagnostic_studies
Limits:
Child
/
Humans
Language:
Ko
Journal:
Allergy, Asthma & Respiratory Disease
Year:
2017
Type:
Article