The Impact of Menopause on Bone Fusion after the Single-Level Anterior Cervical Discectomy and Fusion
Journal of Korean Neurosurgical Society
; : 496-500, 2013.
Article
in En
| WPRIM
| ID: wpr-118486
Responsible library:
WPRO
ABSTRACT
OBJECTIVE: To evaluate the successful fusion rate in postmenopausal women with single-level anterior cervical discectomy and successful fusion (ACDF) and identify the significant factors related to bone successful fusion in pre- and postmenopausal women. METHODS: From July 2004 to December 2010, 108 consecutive patients who underwent single-level ACDF were prospectively selected as candidates. Among these, the charts and radiological data of 39 women were reviewed retrospectively. These 39 women were divided into two groups : a premenopausal group (n=11) and a postmenopausal group (n=28). To evaluate the significant factors affecting the successful fusion rate, the following were analyzed : the presence of successful fusion, successful fusion type, age, operated level, bone mineral density, graft materials, stand-alone cage or plating with autologous iliac bone, subsidence, adjacent segment degeneration, smoking, diabetes mellitus, and renal disease. RESULTS: The successful fusion rates of the pre- and postmenopausal groups were 90.9% and 89.2%, respectively. There was no significant difference in the successful fusion rate or successful fusion type between the two groups. In the postmenopausal group, three patients (10.8%) had successful fusion failure. In the postmenopausal group, age and subsidence significantly affected the successful fusion rate (p=0.016 and 0.011, respectively), and the incidence of subsidence in patients with a cage was higher than that in patients with a plate (p=0.030). CONCLUSION: Menopausal status did not significantly affect bone successful fusion in patients with single-level ACDF. However, in older women with single-level ACDF, the combination of use of a cage and subsidence may unfavorably affect successful fusion.
Key words
Full text:
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Index:
WPRIM
Main subject:
Smoke
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Menopause
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Smoking
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Bone Density
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Incidence
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Prospective Studies
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Retrospective Studies
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Diskectomy
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Transplants
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Diabetes Mellitus
Type of study:
Incidence_studies
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Observational_studies
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Prognostic_studies
Limits:
Female
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Humans
Language:
En
Journal:
Journal of Korean Neurosurgical Society
Year:
2013
Type:
Article