Efficacy of Two Triple Eradication Regimens in Children with Helicobacter pylori Infection
Journal of Korean Medical Science
; : 1037-1040, 2006.
Article
in En
| WPRIM
| ID: wpr-134480
Responsible library:
WPRO
ABSTRACT
Triple therapy with bismuth subsalicylate, amoxicillin, metronidazole (BAM) or with omeprazole, amoxicillin, clarithromycin (OAC) has been commonly used for the eradication of Helicobacter pylori infection. We compared the efficacy of these triple therapies in children with H. pylori infection. We retrospectively analyzed results in 233 children with H. pylori infection and treated with OAC (n=141) or BAM (n=92). Overall eradication rates of triple therapy with OAC and BAM were 74% and 85%, respectively, which showed no statistical difference. Our study showed that the triple therapy with BAM was more effective for the first-line eradication of H. pylori infection in Korean children, but has no statistical difference with OAC regimen.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Organometallic Compounds
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Bismuth
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Omeprazole
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Salicylates
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Retrospective Studies
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Helicobacter pylori
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Helicobacter Infections
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Treatment Outcome
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Clarithromycin
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Drug Combinations
Type of study:
Observational_studies
Limits:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Male
Language:
En
Journal:
Journal of Korean Medical Science
Year:
2006
Type:
Article