The Relationship between Depression and Alcoholism: A Meta-Analysis / 신경정신의학
Journal of Korean Neuropsychiatric Association
; : 75-81, 2005.
Article
in Ko
| WPRIM
| ID: wpr-139116
Responsible library:
WPRO
ABSTRACT
OBJECTIVES: This study was designed to integrate the results of community based studies which assessed a relationship between depression and alcoholism by meta-analysis. METHODS: We identified the previons studies and included in meta-analysis by searching MEDLINE. Overall, 21 results of the studies for relationship between depression and alcoholism were selected for quantitative meta-analysis. Before the integration of the each effect size of the relationship between depression and alcoholism, a homogeneity test was conducted. For the publication bias, we also conducted the analyses of funnel plot, normal quantile plot, rank correlation test and the fail-safe n. RESULTS: We used the random effect model to estimate the overall effect size, because the homogeneity of studies was rejected in a fixed effect model. Our quantitative meta-analysis yielded that integrated odds ratio between depression and alcoholism was 2.42 (95% C.I. 1.98-2.97). From the results of analyses of the publication bias, the probability of publication bias is considered low. CONCLUSION: The published evidences suggested that there may be a significant positive relationship between depression and alcoholism.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Odds Ratio
/
Publication Bias
/
Depression
/
Alcoholism
Type of study:
Etiology_studies
/
Systematic_reviews
Language:
Ko
Journal:
Journal of Korean Neuropsychiatric Association
Year:
2005
Type:
Article