The Molecular Pathogenesis of Pituitary Adenomas: An Update
Endocrinology and Metabolism
;
: 245-254, 2013.
Article
in English
| WPRIM
| ID: wpr-141196
ABSTRACT
Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects and inappropriate secretion of pituitary hormones. Understanding the etiology of pituitary tumorigenesis will facilitate the development of satisfactory treatment for pituitary adenomas. Although the pathogenesis of pituitary adenomas is largely unknown, considerable evidence indicates that the pituitary tumorigenesis is a complex process involving multiple factors, including genetic and epigenetic changes. This review summarized the recent progress in the study of pituitary tumorigenesis, focusing on the role of tumor suppressor genes, oncogenes and microRNAs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oncogenes
/
Pituitary Hormones
/
Pituitary Neoplasms
/
Brain Neoplasms
/
Cell Cycle
/
Cell Transformation, Neoplastic
/
Genes, Tumor Suppressor
/
MicroRNAs
/
Epigenomics
Type of study:
Etiology study
Language:
English
Journal:
Endocrinology and Metabolism
Year:
2013
Type:
Article
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