Usefulness of the Controlled Attenuation Parameter for Detecting Liver Steatosis in Health Checkup Examinees
Gut and Liver
; : 405-410, 2015.
Article
in En
| WPRIM
| ID: wpr-142462
Responsible library:
WPRO
ABSTRACT
BACKGROUND/AIMS:
The controlled attenuation parameter (CAP) implemented in FibroScan(R) is reported to be a non-invasive means of detecting steatosis (>10% steatosis). We aimed to evaluate the usefulness of CAP in detecting steatosis among health checkup examinees and to assess its correlation with ultrasonography (US).METHODS:
Consecutive CAP results were retrospectively collected. A total of 280 subjects were included.RESULTS:
Fatty liver was detected in 119 subjects (42.5%) by US, whereas it was detected in 160 subjects (57.1%) by the CAP. The numbers of subjects with S0S1S2S3 steatosis according to the CAP value were 120595843, respectively. The mean CAP values were 203.34+/-28.39 dB/m for S0, 248.83+/-6.14 dB/m for S1, 274.33+/-8.53 dB/m for S2, and 322.35+/-22.20 dB/m for S3. CAP values were correlated with body weight (r=0.404, p<0.001), body mass index (r=0.445, p<0.001), and the fatty liver grade by US (r=0.472, p<0.001). Among the 161 subjects with normal US findings, steatosis was detected in 65 subjects (40.4%) using the CAP.CONCLUSIONS:
The CAP seems to be useful for detecting very low-grade hepatic steatosis in health checkup examinees. Its role in predicting subjects with a risk of metabolic derangement needs to be evaluated.Key words
Full text:
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Index:
WPRIM
Main subject:
Physical Examination
/
Severity of Illness Index
/
Body Weight
/
Body Mass Index
/
Predictive Value of Tests
/
Retrospective Studies
/
ROC Curve
/
Elasticity Imaging Techniques
/
Fatty Liver
/
Liver
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Screening_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Gut and Liver
Year:
2015
Type:
Article