Capillary-free Vascularized Retina in Patients with Aggressive Posterior Retinopathy of Prematurity and Late Retinal Capillary Formation
Korean Journal of Ophthalmology
; : 109-115, 2013.
Article
in En
| WPRIM
| ID: wpr-143905
Responsible library:
WPRO
ABSTRACT
PURPOSE:
To report the clinical features, clinical course, and treatment outcomes after laser photocoagulation in infants with aggressive posterior retinopathy of prematurity (APROP) and capillary-free zones in vascularized retina.METHODS:
Six patients (12 eyes) with APROP and capillary-free zones in vascularized retina were retrospectively reviewed. Twelve eyes of six infants were included and were treated with laser photocoagulation for avascular retina and for capillary-free zones in vascularized retina, except for the posterior pole, and fundus findings were photographically-documented in sequence. In addition, anatomic and visual outcomes were evaluated with complications of APROP.RESULTS:
Among all of the consecutive infants with APROP, capillary-free zones in vascularized retina were demonstrated in 24% of the infants. All of the infants were >27 weeks of gestation age and had birth weights >1,000 g. After laser treatment, 7 eyes (58.3%) had favorable outcomes, and late capillary filling in capillary-free zones of vascularized retina were noted, however 4 eyes (33.3%) progressed to retinal detachment and 1 eye (8.3%) was complicated by a retinal fold-distorting posterior pole. The visual outcomes were associated with anatomic outcomes.CONCLUSIONS:
The anatomic outcomes in infants with APROP who had capillary-free zones were comparable to previously reported infants with APROP. The late capillary filling of capillary-free zones in vascularized retina was noted, and angiogenesis was considered to be involved. This process toward normal capillary formation or neovascularization in APROP, might determine its outcome.Key words
Full text:
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Index:
WPRIM
Main subject:
Retina
/
Retinal Vessels
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Retinopathy of Prematurity
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Capillaries
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Retrospective Studies
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Treatment Outcome
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Laser Coagulation
Type of study:
Observational_studies
Limits:
Female
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Humans
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Infant
/
Male
Language:
En
Journal:
Korean Journal of Ophthalmology
Year:
2013
Type:
Article