Recurrent Annular Erythema in the Patients with Sj gren's Syndrome and/or Lupus Erythematosus-like Features / 대한피부과학회지
Korean Journal of Dermatology
; : 1552-1558, 2004.
Article
in Ko
| WPRIM
| ID: wpr-147536
Responsible library:
WPRO
ABSTRACT
BACKGROUND: Recurrent annular erythema associated with anti-Ro (SSA) or anti-La (SSB) antibodies has been recognized as a unique cutaneous manifestation of Sj gren's syndrome or Sj gren's syndrome/SLE overlap syndrome in Orientals. OBJECTIVE: The purpose of this study was to evaluate the clinical, histological and serological aspects of recurrent annular erythema in the korean patients with Sj gren's syndrome and/or lupus erythematosus-like features. METHODS: This clinical investigation was carried out on 6 outpatients with this disorder who had visited Department of Dermatology, Seoul National University Hospital, from January 1996 to December 2003. RESULTS: These patients (four females, two males; range of age, 24-60 years, median 45 years) had relatively well demarcated annular erythematous plaques mainly on trunk and extremities. Two-thirds of the patients were anti-Ro positive and one-third was anti-La positive. Biopsy specimens revealed a moderate degree of perivascular and periappendageal lymphocytic infiltration throughout dermis. Other features to suggest LE were not demonstrated. Four patients were treated with oral hydroxychloroquine with good response. CONCLUSION: Although all 6 patients showed annular erythema associated with anti-Ro or anti-La antibodies, only two could be diagnosed as Sj gren's syndrome/SLE overlap syndrome. The other four presented with LE-like features such as photosensitivity, nephropathy and arthralgia.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Outpatients
/
Biopsy
/
Arthralgia
/
Dermis
/
Dermatology
/
Erythema
/
Extremities
/
Seoul
/
Hydroxychloroquine
/
Antibodies
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Ko
Journal:
Korean Journal of Dermatology
Year:
2004
Type:
Article