Changes In The Distribution of Oxytocin and Vasopressin-Immunoreactive Neurons In the Hypothalamic Area of Normal and Hypophysectomized Rats / 체질인류학회지
Korean Journal of Physical Anthropology
; : 33-44, 1999.
Article
in Ko
| WPRIM
| ID: wpr-150969
Responsible library:
WPRO
ABSTRACT
The localization and number of oxytocin- and vasopressin-immunoreactive neurons (OXY-IR & VP-IR) and their fibers in the hypothalamic areas (supraoptic nucleus, paraventricular nucleus, lateral hypothalamic area and median eminence) of the hypophysectomized rat were compared with normal rats at 6 months of survival after surgery at the light microscopic level. The number of VP-IR neurons was markedly decreased in the supraoptic nucleus (SON) and paraventricular nucleus (PVN) in the hypophysectomized rats as compared to normal rats. Moreover, The number of VP-IR fibers was decresed in the SON, PVN, lateral hypothalamic area (LHA) and median eminence in the hypophysectomized rats. The number of OXY-IR neurons and thier fibers were also decreased in the SON and PVN in the hypophysectomized rats. The present results demonstrate that hypophysectomy induces a significant decrease in the number of OXY- and VPIR neurons and fibers within hypothalamic areas (SON, PVN, and LHA at 6 months of post-hypophysectomy) are decreased.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Paraventricular Hypothalamic Nucleus
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Supraoptic Nucleus
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Oxytocin
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Vasopressins
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Immunohistochemistry
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Hypophysectomy
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Hypothalamic Area, Lateral
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Median Eminence
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Neurons
Limits:
Animals
Language:
Ko
Journal:
Korean Journal of Physical Anthropology
Year:
1999
Type:
Article