Relationship between Metabolic Syndrome and Bone Mineral Density in Middle-aged Women / 대한폐경학회지
The Journal of Korean Society of Menopause
; : 142-147, 2010.
Article
in Ko
| WPRIM
| ID: wpr-153600
Responsible library:
WPRO
ABSTRACT
OBJECTIVES:
To determine the relationship between metabolic syndrome (MS) and bone mineral density (BMD) in middle-aged women.METHODS:
Three hundred eight premenopausal women were included in this study, including 268 women without MS and 40 women confirmed to have MS according to the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) criteria. Clinical markers including anthropometric parameters, the serum lipid profile, and glucose level were determined and analyzed with the BMD at the lumbar spine and femoral neck.RESULTS:
There was no significant difference in femoral neck or lumbar BMD between the controls and women with MS. In correlation tests, the body mass index (BMI) showed a significant association with the femoral (r = 0.209, P < 0.001) and lumbar BMD (r = 0.176, P = 0.002). In addition, the waist circumference (WC) was also significantly correlated with the femoral (r = 0.142, P = 0.012) and lumbar BMD (r = 0.113, P = 0.048).CONCLUSION:
The BMI and WC showed a significant positive association with the femoral and lumbar spine BMD in premenopausal women. Further studies with a large population will be needed to elucidate the combined effect of MS on BMD in middle-aged women.Key words
Full text:
1
Index:
WPRIM
Main subject:
Spine
/
Biomarkers
/
Body Mass Index
/
Bone Density
/
Cholesterol
/
Waist Circumference
/
Femur Neck
/
Glucose
Limits:
Female
/
Humans
Language:
Ko
Journal:
The Journal of Korean Society of Menopause
Year:
2010
Type:
Article