Lymphomatoid Granulomatosis: CT and FDG-PET Findings
Korean Journal of Radiology
; : 671-678, 2011.
Article
in En
| WPRIM
| ID: wpr-155127
Responsible library:
WPRO
ABSTRACT
OBJECTIVE: Lymphomatoid granulomatosis (LG) is a rare, aggressive extranodal Epstein-Barr virus (EBV)-positive B-cell lymphoproliferative disease. The purpose of our study was to analyze the CT and fluorodeoxyglucose positron emission tomography (FDG-PET) findings of pulmonary LG. MATERIALS AND METHODS: Between 2000 and 2009, four patients with pathologically proven pulmonary LG and chest CT were identified. Two of these patients also had FDG-PET. Imaging features of LG on CT and PET were reviewed. RESULTS: Pulmonary nodules or masses with peribronchovascular, subpleural, and lower lung zonal preponderance were present in all patients. Central low attenuation (4 of 4 patients), ground-glass halo (3 of 4 patients), and peripheral enhancement (4 of 4 patients) were observed in these nodules and masses. An air-bronchogram and cavitation were seen in three of four patients. FDG-PET scans demonstrated avid FDG uptake in the pulmonary nodules and masses. CONCLUSION: Pulmonary LG presents with nodules and masses with a lymphatic distribution, as would be expected for a lymphoproliferative disease. However, central low attenuation, ground-glass halo and peripheral enhancement of the nodules/masses are likely related to the angioinvasive nature of this disease. Peripheral enhancement and ground-glass halo, in particular, are valuable characteristic not previously reported that can help radiologists suggest the diagnosis of pulmonary LG.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Biopsy, Needle
/
Tomography, X-Ray Computed
/
Radiopharmaceuticals
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Fluorodeoxyglucose F18
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Positron-Emission Tomography
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Lung Neoplasms
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Lymphomatoid Granulomatosis
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Adult
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Humans
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Male
Language:
En
Journal:
Korean Journal of Radiology
Year:
2011
Type:
Article